Projects

>> Industrial Biotechnology
>> Applied Microbiology
>> HPLC
>> Enzymology
>> Fermentation Technology
>> Plant Biotechnology
>> Molecular Biology
>> Bioinformatics

Industrial Biotechnology

Industrial Biotechnology is the application of Biotechnology for industrial purposes involving sustainable production of industrially useful products like biochemicals, biomaterials and biofuels from renewable resources, using living cells and / or their enzymes. It also involves large-scale fermentation as is used in some pharmaceutical production. Industrial Biotechnology is mainly based on fermentation technology and biocatalysis. The use of fermenter is not only in production but also in standardization where optimizations of production processes are done to achieve maximum yield since the industrial profit hovers around the criteria of maximum output with minimum input. Immobilization is a break through technology in this arena which allows economical enzyme aided fermentation with reusability of used enzyme and reduced down streaming.

Projects offered

•Isolation, screening, biochemical characterization, media optimization, shake flask production, pilot scale
 production, downstream processing immobilization and enzyme kinetics of any of the enzymes listed:
oAmylase, protease, cellulase, pectinase, lipase, endoglucanase, invertase etc
•Production of various industrially important microbial products
oEnzymes, vitamins, antibiotics, organic acids, alcohols, wine, bacteriocins, single cell proteins etc
•Production of various medically important microbial products
oMycotoxins, pigments etc
•Strain improvement of industrially important microorganisms
•Immobilization studies of various enzymes
oLarge scale production of enzyme, purification, quantification, immobilization, and comparative studies
•Production and assay of biofertilizers
oRhizobium , Azotobacteo, Azospirillum, Cyanobact, Liquid manure etc

Applied Microbiology

Applied microbiology is an actively researched multi-disciplinary field which is advancing continually. Environmental microbiology involves the study of the composition and physiology of microbial communities in the environment. Medical microbiology deals with the study of pathogens which are of medical importance. Microorganisms are beneficial for biodegradation or bioremediation of domestic, agricultural and industrial wastes and subsurface pollution in soils, sediments and marine environments.

Projects offered

•Effects of heavy metals on microbial growth
oLead, mercury, chromium, cadmium, arsenic, copper and tin etc
•Bacteriophage Studies
oIsolation of bacteriophages, plaque assay, purification of phages
•In vitro antimicrobial studies of various phytochemical compounds
oExtraction, antimicrobial assay and purification of compounds
•Microbiological and chemical analysis of various compounds (case studies)
oMilk, water, eatables, cosmetics, effluents etc
•Microbial degradation of environmentally hazardous compounds
oMycotoxins, dyes, petroleum compounds, plastics, heavy metals etc

HPLC

The need for high-resolution separation methods for analytical and preparative purposes is growing by the minute in the industries and research areas. HPLC is a state-of-the-art technique that is ideal for such requirements due to its precision, sensitivity and reproducibility. GENOHELIX offers HPLC training involving qualitative and quantitative analysis of samples like antibiotics, pesticides etc. at different levels.

Project offered

•Method development for antibiotics using HPLC
•Method development for agrochemicals using HPLC
•Method development for proteins using HPLC

ENZYMOLOGY

Enzymes are the biomolecule which catalyses the biological reactions. They play a key role in all biological reactions and thus, are important tool to analyse the cellular functions.

Enzymology deals with enzyme characterization and the kinetic study. It enables us to find new druds which can inhibit or accelerate a biological reactions. Many enzymes are directly used in industrial process based on their characteristics and kinetics in in vitro conditions.

Projects offered 

• Enzyme characterization and kinetic studies
• Study of inhibition kinetics of an enzyme
• Screening of different organic/inorganic compounds as inhibitors for the enzymes
• Immobilization of enzymes/ cells
• Comparative study of immobilized and free enzymes
• Screening and quantification of different enzymes from single source

PLANT BIOTECHNOLOGY

Plant Biotechnology is a rapidly expanding discipline. It chiefly involves the introduction of foreign genes into economically important plant species, resulting in crop improvement and the production of novel plants. Plant Biotechnology has many applications in the field of medicine, environment, food, farming and pharmaceutical industries.

Projects offered

• Studies on induction of organogenesis in various plant species
• Studies on induction of somatic embryos in various plant species
• Studies on selection and screening of stress tolerant food crops
• Studies on somaclonal variation in various plant species
• Production of plant secondary metabolites
• Agrobacterium mediated gene transformation in plants
• Mutagenic studies in plants and confirmation of mutation through DNA fingerprinting
• Phytoremediation
• Cost effective media formulations for plant tissue culture.
• In vitro study of effectiveness of biofertilizers.


MOLECULAR BIOLOGY

Molecular Biology is the study of biological molecules and the molecular basis of structure and function in living organisms. Ever since the revolution in experimental biology occurred, the techniques in molecular biology and genetic engineering have been at the forefront and is still contributing immensely to the research being carried out globally

Projects offered

•Gene Cloning
o Prokaryotic genes
oEukaryotic genes
ocDNA cloning
oTA cloning
•Expression, purification & detection of proteins
•Expression studies of cloned genes
•DNA fingerprinting using
oRAPD method
oISSR method
•Identification of SNP (Single nucleotide polymorphism) by PCR-RFLP
•PCR based molecular diagnostics
oERIC PCR
oIdentification of micro organisms using multiplex PCR
•Microbial identification by 16s rDNA analysis
•Mutational studies and molecular characterization of mutants

BIOINFORMATICS

Bioinformatics is the application of computer technology to the management of biological data. The data for analysis is obtained from techniques like DNA/protein sequencing, X-Ray crystallography, gene expression studies etc. Analysis of such data includes identifying genes, detecting motifs of functional significance, predicting structure from sequence, studying evolutionary relationships etc. It is a rapidly developing branch of biology and is highly interdisciplinary, using techniques and concepts from informatics, statistics, mathematics, chemistry, biochemistry, physics, and linguistics. It has many practical applications in different areas of biology and medicine.

Projects offered

•Homology modeling and structure analysis
•Sequence analysis
•Phylogenetic analysis